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January 1, 2022Polish Journal of Cardio-Thoracic SurgeryOpen Access

Surgical treatment of primary cardiac tumors:20-year single center experience

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Why the study?

Does surgical resection improve long-term survival in patients with primary cardiac tumors compared to the general population?

Design

Single-center retrospective analysis

Follow-up

Up to 15 years postoperatively

Key result

Surgical resection of primary cardiac tumors resulted in long-term survival up to 15 years that was comparable to the age- and sex-matched general population (relative survival 0.91).

Authors

MDMartin DěrgelJGJán GofusPSPetr Smolák

Discussion

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Overview

Supports resection decisions in operable primary cardiac tumors; leaves open need for prospective confirmation in malignant cases.

Study Design

Type

Observational (n=60)

Multicenter

No

Structured PICO

Does surgical resection improve long-term survival in patients with primary cardiac tumors compared to the general population?

P
Population
60 patients (median age 64, 53.3% female) undergoing surgical resection for primary cardiac tumors, followed for a mean of 8.5 years.
I
Intervention
Surgical resection of primary cardiac tumor (mostly via standard median sternotomy on mild hypothermic cardiopulmonary bypass with cardioplegic cardiac arrest).
C
Comparator
Age- and sex-matched general population (for long-term survival comparison).
O
Outcome
Short- and long-term outcomes (perioperative mortality, complications, and long-term survival up to 15 years postoperatively).hard clinical

Main Result

Effect estimate: relative survival 0.91 (95% CI 0.68-1.23)

Surgical resection of benign primary cardiac tumors yields excellent long-term survival comparable to the general population, whereas malignant tumors have a poor prognosis.

Limitations

  • Retrospective observational single center study
  • Relatively low number of patients
  • Only a single case of sarcoma recorded
  • retrospective observational single center study
  • relatively low number of patients
  • only a single case of sarcoma

Cite This Study

Děrgel et al. (2022) conducted an observational in Primary cardiac tumors (n=60). Surgical resection vs. Age- and sex-matched general population was evaluated on Long-term relative survival at 15 years (relative survival 0.91, 95% CI 0.68-1.23). Surgical resection of primary cardiac tumors resulted in long-term survival up to 15 years that was comparable to the age- and sex-matched general population (relative survival 0.91).

synapsesocial.com/papers/6a2078e421cb8130ca780454https://doi.org/10.5114/kitp.2022.114553
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