Key result
Percutaneous MCS provides rapid hemodynamic support in acute compromise, counterbalanced by device-specific complications.
Why the study?
Percutaneous mechanical circulatory support devices have rapidly evolved with diverse designs and clinical applications, necessitating a comprehensive synthesis of current knowledge on their mechanisms, clinical utility, and limitations.
This review provides a comprehensive summary of the mechanisms, clinical utility, advantages, and limitations of contemporary percutaneous mechanical circulatory support devices for acute hemodynamic compromise.
May inform individualized device selection in acute settings; leaves open comparative efficacy from randomized trials.
Mechanical circulatory support devices have become essential in the management of acute hemodynamic compromise, providing rapid, minimally invasive augmentation of cardiac output in heart failure, cardiogenic shock, high-risk percutaneous coronary intervention, post-cardiotomy ventricular dysfunction, and refractory cardiac arrest. Unlike conventional ventricular assist systems, percutaneous mechanical circulatory support devices are designed for swift deployment through peripheral vascular access and are intended for short-term support. Advancements over recent decades have substantially broadened the range of these devices. They vary widely in mechanism of action, flow capability, insertion technique, and hemodynamic targets, allowing tailored support for left-, right-, or biventricular failure. Parallel to technological innovation, evidence from major trials and international registries has refined contemporary practice by characterizing hemodynamic benefits, procedural outcomes, and device-specific limitations. This review synthesizes contemporary knowledge on pMCS systems, their designs, physiological effects, clinical indications, and limitations.
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Shetty et al. (2026) conducted a review in Advanced heart failure and acute hemodynamic compromise. Percutaneous mechanical circulatory support (pMCS) devices was evaluated. Percutaneous mechanical circulatory support devices provide rapid, minimally invasive augmentation of cardiac output in acute hemodynamic compromise, though limited by device-specific complications.
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