Key result
Commissural symmetry and circumferential annuloplasty drive durable bicuspid aortic valve repair.
Why the study?
Bicuspid aortic valve-related aortic regurgitation presents heterogeneous anatomic phenotypes complicating durable valve repair, necessitating standardized, phenotype-driven repair strategies in specialized aortic centres.
Does a standardized, phenotype-driven surgical repair strategy improve long-term durability and outcomes in patients with bicuspid aortic valve regurgitation?
Does a standardized, phenotype-driven surgical repair strategy improve long-term durability and outcomes in patients with bicuspid aortic valve regurgitation?
A phenotype-driven approach to bicuspid aortic valve repair, emphasizing complete circumferential annular stabilization and geometric symmetry, yields excellent long-term durability and informs a standardized surgical decision-making algorithm.
Bicuspid aortic valve (BAV)-related aortic regurgitation presents heterogeneous anatomic phenotypes that complicate durable valve repair. To ensure repair reproducibility, current guidelines recommend specialised aortic centres with transparent, published outcomes. This report summarizes the two-decade experience of a single Polish aortic centre integrating clinical, imaging, and surgical data to develop a standardized, phenotype-driven repair strategy. Across these institutional studies, commissural symmetry and circumferential annuloplasty consistently emerged as key determinants of durable repair, while advanced imaging demonstrated the superiority of complete annular stabilization over subcommissural techniques. Additional experience with valve-sparing root procedures and geometric ring annuloplasty in highly asymmetric BAVs further contributed to a unified treatment approach. Synthesizing these findings, the review presents a phenotype-driven decision-making algorithm developed at the centre to guide the selection of repair techniques and root interventions, with the aim of standardizing and optimizing long-term outcomes.
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Jasiński et al. (2026) conducted a review in Aortic regurgitation in patients with a bicuspid aortic valve. Phenotype-driven aortic valve repair was evaluated. Commissural symmetry and circumferential annuloplasty consistently emerged as key determinants of durable bicuspid aortic valve repair, supporting a standardized phenotype-driven decision-making algorithm.
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