Key result
Early palliative care optimizes quality of life and minimizes futile interventions in TAVI-ineligible severe AS.
Why the study?
Optimal timing and practical guidance for referring patients disqualified from TAVI to palliative care are needed to support Heart Team decision-making.
Early integration of structured palliative care for patients disqualified from TAVI can optimize symptom relief, align treatment with patient goals, and prevent futile medical interventions.
This narrative review examines when patients disqualified from transcatheter aortic valve implantation (TAVI) should be referred to palliative care, offering practical guidance for Heart Team decision-making. A targeted search of PubMed and Scopus (2010-2025) was conducted, integrating palliative care practice and brief clinical vignettes. Recurrent triggers for palliative referral include advanced frailty likely to limit recovery, multimorbidity with refractory symptoms, patient or family preference for comfort-focused treatment, and anatomical or physiological unsuitability for TAVI confirmed by a multidisciplinary Heart Team. Best-practice themes include early symptom-directed pharmacotherapy, comprehensive psychosocial and spiritual support, explicit documentation of care goals, and coordinated transitions to community or home-based services. Early, structured collaboration among cardiology, cardiac surgery, and palliative medicine can optimise quality of life, minimise futile interventions, and ensure continuity of care in patients with TAVI-ineligible severe aortic stenosis. Prospective studies should validate integration models and quality indicators to ensure their effectiveness.
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Woźniak et al. (2026) conducted a review in Severe aortic stenosis. Palliative care integration was evaluated. Early integration of palliative care for patients with severe aortic stenosis disqualified from TAVI can optimize quality of life and minimize futile interventions.
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