Figure S4 from Single-Cell Analysis of Posttranslational Modifications Identifies Immunosuppressive Macrophage Subtypes in the HBV-Positive Hepatocellular Carcinoma Microenvironment

Key Points

• MAIN FINDING: Immunosuppressive macrophage subtypes are identified in the HBV-positive hepatocellular carcinoma microenvironment.
• KEY EVIDENCE: Levels of phosphorylated HSP27, STAT1, and TRIM28 were examined in tumor-associated macrophages (TAMs).
• APPROACH: The study employed single-cell analysis to investigate posttranslational modifications in macrophages.
• SIGNIFICANCE: Understanding these macrophage subtypes may inform new treatment strategies targeting immunosuppression in liver cancer.