Table S1 from RGN6024 Is a Brain-Penetrant, Small-Molecule Tubulin Destabilizer for the Treatment of Glioblastoma

Key Points

• MAIN FINDING: RGN6024 significantly decreases viability in glioblastoma cell lines compared to controls.
• KEY EVIDENCE: In tested cancer cell lines, RGN6024 demonstrated superior tubulin destabilizing effects.
• APPROACH: The study evaluated the impact of RGN6024 and RGN3067 on various cancer cell lines.
• SIGNIFICANCE: This research highlights a promising small-molecule option for glioblastoma treatment, advancing therapeutic strategies.