Supplemental Figure 1 from Nanobody-Directed CEA-Targeting CAR T Cells Eliminate Gastrointestinal Cancer Xenografts

Key Points

• Main finding highlights the effectiveness of CAR T cells targeting CEA in gastrointestinal cancer models.
• Evidence from nucleotide and amino acid sequences substantiates the role of the nanobody VHHB30 in this therapy.
• Approach involves generating nanobody-directed CAR T cells and evaluating their effectiveness against cancer xenografts.
• Significance lies in potential advancements in targeted therapies for challenging gastrointestinal cancers, offering new hope for patients.