Sarcoidosis is a systemic granulomatous disease which may affect the skin in about one-third of patients. It is characterised by the histopathological finding of non-caseating granulomas. There is a predilection for cutaneous sarcoidosis towards prior trauma sites. Tattoo-associated sarcoidosis may be caused by the injected foreign pigment or its by-products. These reactions are commonly observed with black and red dyes, although other colours have been implicated. Currently, there are no evidence-based treatment regimens of tattoo sarcoidosis; however, the most commonly used treatments leading to clinical improvement in both symptoms and tattoo appearance include systemic steroids followed by immunosuppressive agents like methotrexate. We present a case of a woman with a history of pulmonary and cutaneous sarcoidosis found to have sarcoidosis within her tattoo who was successfully treated with hydroxychloroquine monotherapy, without preceding systemic corticosteroids.
Sekeramayi et al. (Sat,) studied this question.
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