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August 18, 2025

Invasive Adenocarcinoma and Clear Cell Stromal Tumor Coexisting in FDG-Avid Pulmonary Cystic Lesions

PTPan TangChinese Academy of Medical Sciences & Peking Union Medical College LYLixiang YangWuxi People's Hospital RTRong TianSichuan University

Key Points

Invasive adenocarcinoma was confirmed in the left lower lobe cystic lesion, indicating a challenging diagnosis.
The right upper lobe cystic lesion was diagnosed as a benign clear cell stromal tumor, revealing its rarity.
Utilizing PET/CT imaging helped identify FDG-avid pulmonary lesions, which are critical for diagnosis.
This case emphasizes the importance of accurate pathology in differentiating between malignant and benign tumors.

Abstract

We present a diagnostically challenging case involving a 50-year-old woman with 2 FDG-avid cystic pulmonary lesions identified on PET/CT. The left lower lobe lesion, showing moderate FDG uptake, was confirmed by pathology as invasive nonmucinous adenocarcinoma. In contrast, the right upper lobe lesion demonstrated higher avidity than the one in the left lung but was ultimately diagnosed as a rare benign clear cell stromal tumor.

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Cite This Study

Tang et al. (Mon,) studied this question.

synapsesocial.com/papers/68af4760ad7bf08b1ead46db https://doi.org/https://doi.org/10.1097/rlu.0000000000006089

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