Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder primarily affecting the kidneys and liver, but its systemic nature can lead to unexpected extrarenal findings. This report describes a 55-year-old woman with ADPKD who presented with hypertension and abdominal discomfort. Diagnostic imaging uncovered not only typical renal and hepatic cysts but also rare incidental lesions-a caecal lipoma, ovarian dermoid, and diverticulum. Surprisingly, she later developed synchronous bilateral breast cancer, suggesting a possible link between ADPKD and malignancy. These findings highlight the need for comprehensive evaluation in ADPKD patients, as extrarenal manifestations may signal underlying comorbidities. A multidisciplinary approach is essential for early detection and management of such complex presentations, emphasizing the importance of regular surveillance beyond renal and hepatic involvement.
Srinivas et al. (Thu,) studied this question.