Introduction The integration of Artificial Intelligence (AI) and gamification into higher education is reshaping educational practices by personalizing learning and fostering essential workforce skills. This study critically examines the effectiveness of these technologies, their impact on student engagement, and the factors influencing students’ acceptance. Methods A systematic literature review complemented by Topic Modeling using Latent Dirichlet Allocation (LDA) identified key research themes. Subsequently, predictive modeling with machine learning algorithms, hyperparameter optimization, and Local Interpretable Model-Agnostic Explanations (LIME) were applied to classify academic documents and interpret influential factors. Results Findings indicate that AI effectively customizes educational pathways, enhancing engagement and academic performance. Gamification notably supports soft skill development, providing more interactive assessments than traditional approaches. However, challenges related to data privacy and technological accessibility remain significant, particularly affecting international students and institutions with limited resources. Discussion AI and gamification demonstrate considerable potential for transforming higher education through personalized learning and interactive skill assessments. Nevertheless, widespread adoption depends on addressing data privacy concerns and ensuring technological equity. Future research should investigate the long-term implications of these technologies in developing students’ adaptability within a dynamic global workforce.
Marengo et al. (Mon,) studied this question.