Supplementary Figure S8 from Unraveling Relatlimab-Specific Biology Using Biomarker Analyses in Patients with Advanced Melanoma in RELATIVITY-047 | Synapse
September 10, 2025Open Access
Supplementary Figure S8 from Unraveling Relatlimab-Specific Biology Using Biomarker Analyses in Patients with Advanced Melanoma in RELATIVITY-047
Key Points
Gene signatures were characterized based on treatment arms NIVO + RELA versus NIVO alone, revealing distinct profiles.
Responses categorized as complete response/partial response and progressive disease were analyzed for differences.
Data indicates possible stratification of patients based on gene expression linked to treatment response.
Insights from biomarker analyses may inform future therapeutic strategies for patients with advanced melanoma.
Abstract
Characterization of gene signatures in tumor samples associated with treatment arm, NIVO + RELA (A) versus NIVO (B); and type of response, CR/PR (C) versus PD (D).