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September 10, 2025Open Access

Closure of a large post-endoscopic full-thickness resection defect in the duodenum using a novel through-the-scope twin clip

Key Points

Closure of a defect post-resection was successful, showcasing a potential advancement in endoscopic techniques.
The procedure involved a novel twin clip method to manage a defect following the resection of a 2.5-cm submucosal tumor.
An enhanced computed tomography and endoscopic ultrasound guided the intervention approach, ensuring accurate tumor assessment.
This case illustrates the efficacy of the new technique, suggesting it could enhance the safety of similar procedures in duodenal surgery.

Abstract

A 46-year-old man was admitted to our hospital with a 2.5-cm submucosal tumor in the duodenal bulb (Fig. 1). Enhanced computed tomography revealed a rounded abnormal enhancement in the duodenal bulb (Fig. 2). Endoscopic ultrasound showed a heterogeneous hypoechoic lesion originating from the muscularis propria with both intraluminal and extraluminal growth (Fig. 3). A submucosal injection was performed, followed by a mucosal incision around the intraluminal component of the tumor to expose the pseudocapsule.

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Authors

Yiying Qi

Army Medical University

Aihong Yin

Hongyan Liu

Jinzhou Central Hospital

Journals

Endoscopy

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Closure of a large post-endoscopic full-thickness resection defect in the duodenum using a novel through-the-scope twin clip

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