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Table 4 from Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer | Synapse
September 16, 2025
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Table 4 from Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer
RY
Rona Yaeger
Memorial Sloan Kettering Cancer Center
JM
Jean-François Martini
Pfizer (United States)
LP
Lincoln W. Pasquina
Boston Foundation
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Key Points
Detection of BRAF V600E was significantly improved in colorectal cancer patients, enhancing treatment decisions.
The bridging study subpopulations revealed strong performance metrics for FoundationOne Liquid CDx in identifying BRAF mutations.
Data showed that using the FoundationOne Liquid CDx improves the identification of key mutations in colorectal cancer.
The findings indicate that accurate testing for BRAF V600E may lead to more targeted therapies for colorectal cancer patients.
Abstract
Primary efficacy in the bridging study subpopulations
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Yaeger et al. (Tue,) studied this question.
synapsesocial.com/papers/68d4565b31b076d99fa5b1a7
https://doi.org/https://doi.org/10.1158/2767-9764.30083892