Motivation: The prior knowledge of the latent manifold structure implicit in the imaging principles can be further explored for improved MRF reconstruction. Goal(s): To propose a novel deep-learning framework with manifold structure priors of MRF data and other data priors for improved MRF reconstruction. Approach: We propose a novel deep unrolled network based on manifold structured data regularization in the non-Euclidean norm sense. In addition, we impose additional sparsity constraints on the parameter maps to further improve the accuracy of the manifold structure estimation. Results: Experimental results demonstrate that the proposed method outperforms the original manifold structured data priors-based method and several state-of-the-art methods. Impact: By further incorporating the manifold structure priors along with the data priors in the parameter domain, our method can provide more accurate tissue quantification.
Ji et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: