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Arterial hypertension stands as a primary global contributor to cardiovascular, cerebrovascular, and renal ailments, along with heightened mortality rates. Despite the safety and efficacy of pharmacotherapy in reducing blood pressure (BP) and cardiovascular risk, adequate BP management remains elusive, and mortality rates due to elevated BP continue to rise steadily. To address challenges such as medication non-adherence and low persistence rates, research has explored device-based interventions. Among these, catheter-based renal denervation (RDN) has undergone extensive examination over the past 15 years. This contemporary review article outlines the rationale behind RDN, evaluates existing evidence, offers recommendations for a safe procedure, elaborates a case done by us, and discusses RDN's position in current guidelines and clinical practice.
Balbir Singh (Thu,) studied this question.