September 4, 2024Open Access

The Role of Claudins in the Pathogenesis of Dextran Sulfate Sodium-Induced Experimental Colitis: The Effects of Nobiletin

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Abstract

The pathogenesis of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease is not well understood. This study investigated the roles and regulation of the claudin-1, -2, -3, and -4 isoforms in the pathogenesis of ulcerative colitis, and the potential therapeutic effects of nobiletin.

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Al-Failakawi et al. (Wed,) studied this question.

synapsesocial.com/papers/68e59566b6db643587530a2f https://doi.org/https://doi.org/10.3390/biom14091122

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4Nobiletin acts anti-inflammatory on murine IL-10−/− colitis and human intestinal fibroblasts2018 · 50 citations
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