August 23, 2024Open Access

Clearance of erythrocytes from the subarachnoid space through cribriform plate lymphatics in female mice

AMAdrian MadaraszUniversity of Bern XLXin LiUniversity of Bern SPSteven T. ProulxUniversity of Bern

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Abstract

Atraumatic subarachnoid haemorrhage (SAH) is associated with high morbidity and mortality. Proposed mechanisms for red blood cell (RBC) clearance from the subarachnoid space (SAS) are erythrolysis, erythrophagocytosis or through efflux along cerebrospinal fluid (CSF) drainage routes. We aimed to elucidate the mechanisms of RBC clearance from the SAS to identify targetable efflux pathways.

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Madarasz et al. (Fri,) studied this question.

synapsesocial.com/papers/68e5b277b6db64358754b2e4 https://doi.org/https://doi.org/10.1016/j.ebiom.2024.105295

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