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Perivascular spaces (PVS) dilatation has been recently linked to aging and neurodegenerative diseases. T2-weighted ultra-high field MRI allows to image the PVS burden at high contrast and spatial resolution non-invasively. However, most of sub-voxel sized PVS cannot be resolved due to partial volume effects and remaining signal from blood and tissue. High-resolution 3D-TSE with reduced flip angle allowed the visualization of PVS with a very high CSF-to-tissue ratio of ~37:1 at 7T.
Saïb et al. (Wed,) studied this question.
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