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MRI is a non-invasive method for breast lesions diagnosis. However, some imaging features of benign and malignant lesions in breast are still overlap. APT-weighted imaging (APTw) is a endogenous biomarker that allows non-invasive visualization of tissue composition and microscopic information for mobile proteins and peptides. The present study explores the feasibility of the combination of APT and dynamic contrast-enhanced MR imaging to assess of breast lesions. Results of this study indicate the APT value has significant difference between benign and malignant breast lesions.
Zhuang et al. (Wed,) studied this question.