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In this work, we develop, validate, and apply a novel reconstruction framework for intra-bin correction and inter-bin compensation of respiratory motion in cardiac and respiratory motion-resolved free-running whole heart 5D MRI. We demonstrate respiratory resolved images with reduced artifact and without compressing the underlying physiological motion providing a means to increase the acquired resolution, accelerate the acquisition, or investigate respiratory driven changes in cardiac output and blood flow, potentially leading to new MRI driven biomarkers for cardiovascular disease
Roy et al. (Wed,) studied this question.
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