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We compared multi-echo (mTE) resting-state (rs) fMRI to single-echo (sTE) fMRI for seed-based mapping of seven canonical resting state networks (RSN) in 69 pre-surgical patients. Acquisition parameters were identical except for TE and statistical analyses were constrained by group-specific RSN masks. mTE-rsfMRI showed significantly higher functional-connectivity (fc) for all RSNs, while sTE showed comparatively fewer RSNs with areas of significantly higher fc (PFWE<0.05). Our results suggest that mTE-rsfMRI may be more sensitive than sTE-rsfMRI for mapping of the sensory-motor, default mode, salience, frontoparietal, dorsal attention, language and visual networks in a neurosurgical setting.
Radwan et al. (Wed,) studied this question.
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