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The pursuit of high-spatial-angular-temporal resolution for in vivo diffusion MRI at 7T is challenging, but also receives continuous interest. We hereby propose shift-encoded interleaved EPI and a joint reconstruction technique with LLR regularization. Preliminary results achieve up to 8.7-fold acceleration per shot in 2-shot EPI acquisition with 1.4 mm isotropic nominal resolution. Moreover, with the integrated joint reconstruction for noise reduction, high-quality diffusion-weighted images render more spatially-continuous fiber anisotropy maps and clearer fiber crossing in the fiber orientation distribution function.
Tan et al. (Wed,) studied this question.
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