August 14, 2024

Biventricular and Hemodynamic Assessment under Multi-stage Exercise using Real-time CMR

Key Points

Ejection fraction and cardiac output increase with exercise intensity, showing significant adaptation.
The study involved 12 healthy subjects undergoing multi-stage exercise stress tests using real-time cardiovascular MRI.
Assessment utilized real-time cine and flow data, achieving high acceleration in imaging reconstructions via compressed sensing techniques. Understanding cardiac responses to exercise may enhance fitness evaluations and clinical assessments in longer-term studies.

Abstract

A comprehensive exercise stress cardiovascular MRI (Ex-CMR) was performed in twelve healthy subjects. Biventricular quantification was performed from real-time cine, while hemodynamic parameters in the ascending aorta and main pulmonary artery were estimated using real-time flow. The acquisition process was repeated two to three times at increasing exercise intensities. The highly accelerated (R = 7-8 for cine and R = 16 for flow) real-time data were reconstructed inline using Gadgetron-based compressed sensing reconstruction. In agreement with the literature, the ejection fraction and cardiac output correlated positively with exercise intensity.

Biventricular and Hemodynamic Assessment under Multi-stage Exercise using Real-time CMR

Key Points

Abstract

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