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Observed TE-dependent T1 has been shown to correlate with MRI perfusion scores. Here, 22 patients with COPD were examined using DCE MRI and 2D UTE. Perfusion and T1(TE) was quantified based on these, respectively. Correlations of T1(TE) with perfusion measures were examined, with the strongest inter-patient correlation at TE2=500μs but stronger local correlations at TE1=70μs and TE3=1200μs than at TE2. The average T1 in defect areas according to DCE was shorter than in normal areas, with the smallest difference at TE2. This implies that the local TE-dependence in defect voxels is further away from previously published behaviour in healthy volunteers.
Triphan et al. (Wed,) studied this question.