Primary Radiodiagnosis of Skeletal Changes in the Onset of Multiple Myeloma, Approaches to Differential Radiodiagnosis (Observations from Practice)

Multiple myeloma — Rustitzky-Kahler disease is the most common tumor of the group of Ig-secreting lymphomas. The article presents the difficulties of radiodiagnosis assessment of skeletal changes in the initial stages of multiple myeloma, when bone pain is the only clinical manifestation, and X-ray examination reveals single large foci of destruction. These observations emphasize the important role of assessment and interpretation of bone changes in such situations, which can be the main guiding factor in choosing an examination algorithm for making a correct diagnosis. The article is of interest to radiation diagnosticians, it presents literature data and issues of differential radiodiagnosis of skeletal changes in multiple myeloma.