1930-LB: A Randomized Trial of Real-Time Continuous Glucose Monitoring (RT-CGM) with Culturally Tailored Education for Latino Patients with Type 2 Diabetes (DM)

Background: Culturally tailored diabetes education and RT-CGM both support patients living with DM. However, data on education delivered virtually is limited in the Latino population and few studies have assessed the effect of RT-CGM combined with DM education. Methods: We conducted a study of Latino patients diagnosed with Type 2 DM who were not on intensive insulin therapy. Patients were randomized (1: 1) to virtually delivered sessions (12) of education only or education with cyclic RT-CGM over 12 weeks. The primary outcome was A1c at 12 weeks. Results: 120 participants were randomized to education (59) or education + RT-CGM (61) with 33 in each arm completing 12 weeks of intervention. The mean age was 46 years, 44% were female, 98% preferred Spanish language, 30% had income 25, 000, and 30% had health insurance. Most participants (70%) attended 50% of 12 educational sessions. Mean A1c at baseline was 10. 5 with 74% having A1c 9. 0. A1c improved at 12 weeks by 1. 3mg/dL with education and by 2. 5mg/dL with education + RT CGM, with a difference of 1. 3 (p=0. 012) between groups. Conclusions: Virtually delivered culturally tailored education improved A1c at 12 weeks in both groups, with RT-CGM conferring even greater improvement in A1c over education alone. The use of RT-CGM should be considered as an adjunctive therapy to education early in diabetes. Disclosure N. M. Ehrhardt: Advisory Panel; Bayer Inc. , Dexcom, Inc. Research Support; Dexcom, Inc. , Novo Nordisk. Advisory Panel; Novo Nordisk. Research Support; Merck & Co. , Inc. L. Wright: None. P. Berberian: None. E. Jones: None. A. Vasconcelos: None. B. A. Comstock: None. Funding American Diabetes Association (11-21-ICTSHD-51)