Reduced Radial Artery Occlusion in Transradial Cerebral Angiography: Key Predictive Factors and Preventive Measures from a Single-Center Study of 543 Patients

Background:The transradial approach (TRA) for cerebral angiography and neurointerventional treatment has gained popularity, but the narrow diameter and weak pulsation of the radial artery lower the initial puncture success rate compared to femoral artery puncture.This retrospective study from a single center evaluated the incidence of and factors associated with radial artery occlusion (RAO) in 543 patients who underwent transradial approach (TRA) for cerebral angiography. Material/Methods:We included 543 patients who underwent TRA from July 2021 to February 2024.Ultrasound was used to determine whether the radial artery was occluded.Relevant clinical data were recorded to assess the incidence of and factors affecting RAO. Results:At 24 h after DSA, we performed ultrasound imaging.The patients were divided into an RAO group (n=32) and a non-RAO group (n=511).Results showed that RAO was significantly higher in patients who did not have add heparin to the antispasmodic agents, and they were more likely to have needed more than 3 radial artery puncture attempts, and tended to have received an 11-cm radial artery sheath with the Cordis puncture needles (all P<0.05).Multiple regression logistic analysis showed that adding heparin to the antispasmodic agents (OR=0.076,95% CI: 0.018-0.321,P<0.001), having fewer than 3 radial artery puncture attempts (OR=0.245,95% CI: 0.111-0.541,P<0.001), using a 16-cm radial artery sheath (OR=0.195,95% CI: 0.067-0.564,P=0.003), and using Terumo puncture needles (OR=0.325,95% CI: 0.148-0.717,P=0.005) can reduce the incidence of radial artery occlusion. Conclusions:Our center found that adding heparin to the antispasmodic agents reduced the number of radial artery punctures attempts, and using a 16-cm radial artery sheath significantly lowered the incidence of early RAO after transradial cerebral angiography.