An unusual presentation of fungal brain abscess in immunocompetent host

Focal area of necrosis, with a surrounding membrane within the brain parenchyma, usually resulting from an infectious process or rarely from a traumatic process known as brain abscess. We report a case of young female, who presented with multiple abscess in left frontal and right occipital region of brain, she was otherwise immunocompetent, lacking any known risk factor for opportunistic infection. And this fungal abscess manifest with unusual presentation of bilateral lower limb weakness along with seizures and fever. This infection leads to acute kidney injury (AKI), necessitating kidney replacement therapy (RRT) in term of intermittent hemodialysis (IHD). After drainage of abscess and antifungal therapy, she responded well, her acute kidney injury resolved and she showed clinical and radiological improvement. doi: https://doi.org/10.12669/pjms.40.6.8877 How to cite this: Bhatti SI, German S, Waqar T, Naqvi R. An unusual presentation of fungal brain abscess in immunocompetent host. Pak J Med Sci. 2024;40(6):1306-1309. doi: https://doi.org/10.12669/pjms.40.6.8877 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.