Knowledge and trust of mothers regarding childhood vaccination in Rwanda

Abstract Introduction Knowledge and trust are some of the contributing factors to vaccine acceptance (VA) and Vaccine hesitancy (VH) is one of the top threats to global health. A significant drop in childhood vaccination has been observed in recent years. One important reason that influences mothers' choice to either postpone or avoid children's vaccinations is knowledge and trust in childhood vaccines. This study aimed to assess mothers' knowledge and trust on vaccination of their children, and to examine the association between vaccination knowledge and selected socio-demographic factors. Methods A cross-sectional survey was conducted from January 2022 to March 2022 to assess the knowledge and trust of mothers regarding childhood vaccination. Data was collected with self-administered questionnaires. Multivariable logistic regression analysis was employed to assess factors associated with childhood vaccine knowledge and trust. Results Of the 2, 126 Rwandan parents who participated in the study, the proportions with good knowledge of – and good trust in childhood vaccination were 95. 5% and 91. 4%, respectively. The popular sources of information about childhood vaccination were health care professionals (91. 8%) and mass media (28. 9%). Multinomial logistic regression analysis showed that good knowledge of – and trust in childhood vaccination were associated with the relationship with child (ren), education, occupation, and monthly income. The Multinomial logistic regression also revealed that the determinants of good knowledge of – and trust in childhood vaccination were; caregiver (p = 4. 0 × 10 –4, adjusted Odds Ratio (aOR) ; 1. 7, 95%C. I; 1. 3 – 2. 3), no formal educational status (p = 3. 3 × 10 –2, aOR; 1. 7, 95%C. I; 1. 0 – 3. 0), the unemployed occupational status (p = 2. 4 × 10 –2, aOR; 1. 2, 95%C. I; 1. 0 – 1. 4), and persons on more than 401 per month (p = 2. 0 × 10 –4, aOR; 3. 5, 95%C. I; 1. 8 – 6. 8). Conclusion The majority of parents in Rwanda had both good knowledge of—and good trust regarding childhood vaccination. Public health strategies to promote vaccination, education programmes as well as improved communication tools between health care professionals/traditional leaders/religious leaders and parents need to be considered to achieve favourable vaccination attitudes and practices for all parents in Rwanda.