MP47-01 PRePED STUDY: A RANDOMISED, DOUBLE-BLIND CONTROLLED TRIAL TO EVALUATE THE EFFICACY OF INTRACAVERNOSAL INFUSION OF PLATELET RICH PLASMA (PRP) AGAINST CONTROL (PLATELET POOR PLASMA) IN THE TREATMENT OF VASCULOGENIC ERECTILE DYSFUNCTION PRELIMINARY RESULTS

You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal control, 14 patients). The mean age of the patients was 58.4 (SD 8.9) years. The interim analysis showed that the rate of responders was much lower than expected and additionally in three patients, plaques in the tunica albuginea were detected during the follow-up. Due to these facts, a futility and safety analysis will be performed and the opinion of the Data Safety Monitoring Board (DSMB) will be sought to decide about the early termination of the trial based on the conditional power of the study to achieve its primary outcome and the detected adverse event. The final results of efficacy and safety will be made public at the late-breaking abstract deadline. CONCLUSIONS: PRP does not appear to be an effective treatment for patients with moderate or severe ED, in addition to being associated with a risk of plaque formation in the tunica albuginea. Source of Funding: Ministry of Economy and Competitiveness and co-financed by FEDER funds, Instituto de Salud Carlos III, PI17/02001, Spanish Government © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e762 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Esaú Fernández Pascual More articles by this author Raphael Curvo More articles by this author Gustavo Centeno Soto More articles by this author Claudio Martínez-Ballesteros More articles by this author Jorge Turo Antona More articles by this author Laura Prieto More articles by this author Joaquín Carballido More articles by this author Cristina Avendaño Solá More articles by this author José Luis Bueno More articles by this author Juan Ignacio Martínez-Salamanca More articles by this author Expand All Advertisement PDF downloadLoading ...