PD28-04 SEVERITY OF PENILE CURVATURE IN PATIENTS WITH PEYRONIE’s DISEASE AND ERECTILE DYSFUNCTION DOES NOT CORRELATE WITH DYNAMIC COLOUR DOPPLER DUPLEX ULTRASOUND PARAMETERS: FINDINGS FROM A REAL-LIFE CROSS-SECTIONAL STUDY

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation I (PD28)1 May 2024PD28-04 SEVERITY OF PENILE CURVATURE IN PATIENTS WITH PEYRONIE's DISEASE AND ERECTILE DYSFUNCTION DOES NOT CORRELATE WITH DYNAMIC COLOUR DOPPLER DUPLEX ULTRASOUND PARAMETERS: FINDINGS FROM A REAL-LIFE CROSS-SECTIONAL STUDY Edoardo Pozzi, Federico Belladelli, Christian Corsini, Alessandro Bertini, Massimiliano Raffo, Fausto Negri, Francesco Cattafi, Marco Oddo, Marco Malvestiti, Riccardo Ramadani, Luigi Candela, Paolo Capogrosso, Luca Boeri, Leutrim Zahiti, Agostino Mattei, Alessia d'Arma, Francesco Montorsi, and Andrea Salonia Edoardo PozziEdoardo Pozzi , Federico BelladelliFederico Belladelli , Christian CorsiniChristian Corsini , Alessandro BertiniAlessandro Bertini , Massimiliano RaffoMassimiliano Raffo , Fausto NegriFausto Negri , Francesco CattafiFrancesco Cattafi , Marco OddoMarco Oddo , Marco MalvestitiMarco Malvestiti , Riccardo RamadaniRiccardo Ramadani , Luigi CandelaLuigi Candela , Paolo CapogrossoPaolo Capogrosso , Luca BoeriLuca Boeri , Leutrim ZahitiLeutrim Zahiti , Agostino MatteiAgostino Mattei , Alessia d'ArmaAlessia d'Arma , Francesco MontorsiFrancesco Montorsi , and Andrea SaloniaAndrea Salonia View All Author Informationhttps://doi.org/10.1097/01.JU.0001009380.44020.d3.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Men presenting with Peyronie's disease (PD) frequently have concomitant or develop erectile dysfunction (ED) over time. Data are lacking concerning how the severity of penile curvature may impact toward haemodynamic parameters at penile dynamic colour Doppler duplex ultrasound (CDDU). METHODS: Complete data from 111 consecutive patients seeking first medical help for PD and concomitant ED were analysed. Comorbidities were scored with Charlson Comorbidity Index (CCI). All patients completed the International Index of Erectile Function (IIEF) at baseline, and ED severity was categorized according to Cappelleri's criteria. CDDU was homogenously performed after intracavernosal injection of alprostadil 20 ug and sexual stimulation in all patients. Vasculogenic ED was defined as a peak systolic velocity (PSV) 35 cm/s. Severe ED (i.e., IIEF-EF<11) was found in 4 (3.6%) patients. Notably, patient with normal CDDU parameters did not differ in terms of median (IQR) severity of the penile curvature 40° (30°- 68.5°) vs. 32.5° (27.5°-51°) (p=0.38) in respect to those with normal CCDU parameters. The two groups did not differ in terms of differences were detected between in terms of age, BMI, CCI, smoking, alcohol consumption, circulating testosterone levels, and IIEF-EF scores. At linear regression analysis, the degree of penile curvature was not associated with PSV at CDDU (Coeff: 0.08, p=0.2). No other variables were found associated with PSV at CDDU. CONCLUSIONS: Our study indicates the lack of a significant correlation between the severity of penile curvature and CDDU parameters in men seeking first medical help for PD and concomitant self-reported ED, with most patients showing normal haemodynamic values despite reporting concomitant ED. These findings emerge to be relevant in terms of management work-up of PD patients in the real-life setting. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e613 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Edoardo Pozzi More articles by this author Federico Belladelli More articles by this author Christian Corsini More articles by this author Alessandro Bertini More articles by this author Massimiliano Raffo More articles by this author Fausto Negri More articles by this author Francesco Cattafi More articles by this author Marco Oddo More articles by this author Marco Malvestiti More articles by this author Riccardo Ramadani More articles by this author Luigi Candela More articles by this author Paolo Capogrosso More articles by this author Luca Boeri More articles by this author Leutrim Zahiti More articles by this author Agostino Mattei More articles by this author Alessia d'Arma More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement PDF downloadLoading ...