Recent Advances in Organocatalytic Synthesis and Catalytic Activity of Substituted Pyrrolidines

Abstract: The emergence of enantioselective organocatalysis as a potent synthetic chemistry strate-gy that supports metal-catalyzed transformations has resulted in the creation of novel procedures for the synthesis of various chiral molecules. Organocatalysis is a desirable method for creating com-plex molecular structures due to its many benefits, including its ease of use, wide availability of cat-alysts and low toxicity. Chemists are actively exploring synthetic methodologies and looking into the applications of pyrrolidine-based organocatalysts. The application of organocatalysts spans a wide range of reaction types, highlighting their ability to participate in a variety of catalytic process-es. The current study offers a succinct summary of the principal strategic methods for producing pyrrolidine-based organocatalysts and demonstrating their usefulness in organic transformations.