FIGURE 1 from Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRPα That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies | Synapse
February 22, 2024Open Access
FIGURE 1 from Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRPα That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies
Key Points
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Abstract
Modeling of interactions between the CD47 F-G loop and the SIRPα IgV domain, with the position of the ESE haplotype residues highlighted (magenta).