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December 4, 2025Open Access

Lactate dehydrogenase and short-term mortality in ICU patients with ischemic stroke: a single-center retrospective analysis of MIMIC-IV

Key Points

Short-term mortality is significantly associated with lactate dehydrogenase levels in critically ill IS patients, indicating their prognostic value.
Patients with high LDH at admission had increased in-hospital and 30-day mortality rates according to the retrospective analysis.
Analysis of data from a single-center ICU evaluated the relationship between LDH levels and mortality outcomes for ischemic stroke.
Findings support the potential use of LDH as an adjunct to established prognostic tools for evaluating stroke patients.

Abstract

Admission LDH levels are independently associated with in-hospital and 30 day mortality among critically ill IS patients and may serve as a potential adjunct to established prognostic tools for early risk stratification. External, multicenter validation is warranted to confirm these findings.

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Authors

Kun Fang

Capital University

Jingrun Li

Capital University

Guangyu Han

Capital University

Journals

European journal of medical research

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Institutions

Capital Medical University

Chinese Institute for Brain Research

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Lactate dehydrogenase and short-term mortality in ICU patients with ischemic stroke: a single-center retrospective analysis of MIMIC-IV

Key Points

Abstract

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Discussion

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