December 10, 2025Open Access

Changes of bone, adipose, and muscle-related body compositions in gastric cancers after gastrectomy using deep learning based automatic segmentation

MXMengying XuSouthwest Forestry University DLDan LiuGuizhou University MZM. ZhangShanghai Jiao Tong University

Key Points

Sarcopenia and osteoporosis markedly increased over 12 months.
Adipose-related body compositions experienced the greatest losses after gastrectomy.
Deep learning was used for automatic segmentation of body compositions.
Findings suggest gender differences impact muscle and adipose losses in gastric cancers.

Abstract

BMD, adipose-related, and muscle-related body compositions showed significant losses over 12 months in GCs underwent gastrectomy. The greatest losses were observed in adipose-related compositions. The proportions of sarcopenia and osteoporosis showed significant increases. Gender, baseline BMI, and gastrectomy differences affected adipose- and muscle-related body composition losses but showed no significant effect on BMD.

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