Abstract Giant retroperitoneal mucinous adenocarcinoma of the appendix is a rare, aggressive malignancy characterized by mucin production and significant mass formation, often complicating early diagnosis due to nonspecific symptoms such as abdominal discomfort. Surgical resection, ranging from appendectomy to more extensive procedures like right hemicolectomy, is the primary treatment approach. This case presents a 53-year-old male with a 38 cm retroperitoneal mucinous adenocarcinoma of the appendix. The patient presented with right-sided flank pain, and subsequent imaging revealed a rapidly enlarging mass. Surgical resection was performed successfully via en-bloc resection with a right hemicolectomy. Postoperative care involved monitoring for complications, with the patient recovering uneventfully. This case highlights the challenges in diagnosing and managing large mucinous neoplasms and the importance of a multidisciplinary approach in ensuring optimal patient outcomes.
Solomon et al. (Sat,) studied this question.