The ECG T-wave amplitude decreased in response to mental stress and varied from nighttime sleep to daytime activity, correlating with changes in cardiac sympathetic activity.
Does ambulatory measurement of ECG T-wave amplitude correlate with preejection period as a measure of cardiac sympathetic nervous system activity in healthy adults?
Ambulatory T-wave amplitude correlates with preejection period and provides a complementary measure of cardiac sympathetic nervous system activity in real-life settings.
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Abstract Ambulatory recording of the preejection period ( PEP ) can be used to measure changes in cardiac sympathetic nervous system ( SNS ) activity under naturalistic conditions. Here, we test the ECG T ‐wave amplitude ( TWA ) as an alternative measure, using 24‐h ambulatory monitoring of PEP and TWA in a sample of 564 healthy adults. The TWA showed a decrease in response to mental stress and a monotonic decrease from nighttime sleep to daytime sitting and more physically active behaviors. Within‐participant changes in TWA were correlated with changes in the PEP across the standardized stressors ( r = .42) and the unstandardized naturalistic conditions (mean r = .35). Partialling out changes in heart rate and vagal effects attenuated these correlations, but they remained significant. Ambulatory TWA cannot replace PEP , but simultaneous recording of TWA and PEP provides a more comprehensive picture of changes in cardiac SNS activity in real‐life settings.
Lien et al. (Wed,) reported a other. The ECG T-wave amplitude decreased in response to mental stress and varied from nighttime sleep to daytime activity, correlating with changes in cardiac sympathetic activity.
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