What question did this study set out to answer?

To examine signs and symptoms of RSV at hospitalization among pediatric and older adult patients.

January 14, 2026Open Access

P-704. RSV Signs and Symptoms at Time of Hospitalization among Pediatric and Adult Population with RSV in two Seasons: A Real-World Data Analysis using Electronic Health Records in the US

Key Points

To examine signs and symptoms of RSV at hospitalization among pediatric and older adult patients.
Retrospective analysis using electronic health records data
Patients hospitalized with RSV were selected based on ICD-9, ICD-10, and SNOMED-CT codes
Patient demographics and signs & symptoms were reviewed and reported by age group
890 pediatric and adult patients analyzed from Season 1 and 661 from Season 2
Common signs and symptoms included cough, hypoxemia, and fatigue
Higher incidence of nasal congestion and fever in pediatric patients compared to older adults
Incidence patterns were consistent across both seasons

Abstract

Abstract Background Respiratory syncytial virus (RSV) is a common respiratory illness, with certain populations at higher risk of severe disease including pediatric patients, older adults, and those with compromised immune systems. The current analyses aim to examine the signs and symptoms (S qualifying once per season) were randomly selected for comprehensive review of S 5; at-risk adults: 18-64, 65+). Results A total of 890 and 661 patients were randomly selected from S1 and S2, respectively. Demographics are presented in Table 1 and S&S are presented in Table 2. Overall S&S incidence in children and adults had overlapping similarities, with common S&S (e.g. cough, altered breathing sounds, hypoxemia) found in all age groups. Certain S&S were higher among pediatric patients (e.g. nasal congestion, fever, appetite loss/feeding problems) while other S&S were higher in older adults (e.g. fatigue). Incidence patterns were similar between both seasons of the predominant S&S found across age groups. Conclusion This real-world analysis of RSV patients revealed some overlapping similarities of RSV S&S present at the point of hospitalization. Further characterization of RSV signs & symptoms can help inform natural history of the disease and timely interventions. Disclosures Sima S. Toussi, MD, Pfizer: Stocks/Bonds (Private Company) Negar Niki Alami, MD, Pfizer: Employee|Pfizer: Stocks/Bonds (Public Company) Edward Weinstein, MD, PhD, Pfizer: Employee|Pfizer: Stocks/Bonds (Public Company) Lulu Lee, PhD, Oracle Life Sciences: Employed by Oracle Life Sciences, which received funding from Pfizer to conduct the study. Stacey Purinton, MSN, MPH, Oracle Life Sciences: Employed by Oracle Life Sciences, which received funding from Pfizer to conduct the study. Vicky W. Li, MPH, Oracle Life Sciences: Employed by Oracle Life Sciences, which received funding from Pfizer to conduct the study. Robert J. Taylor, AS, Oracle Life Sciences: Employed by Oracle Life Sciences, which received funding from Pfizer to conduct the study. Neelanzana Paudel, MS, Oracle Life Sciences: Employed by Oracle Life Sciences, which received funding from Pfizer to conduct the study. Wing Yu Tang, MPH, Pfizer: Employee|Pfizer: Stocks/Bonds (Public Company)

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Cite This Study

Toussi et al. (Thu,) studied this question.

synapsesocial.com/papers/6966f31d13bf7a6f02c00cc6 https://doi.org/https://doi.org/10.1093/ofid/ofaf695.916

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