Internal validation protocol for large collaborative clinical data sets: assessment of the CONGRESS database

Key Points

• The aim is to establish a protocol for validating large clinical data sets to enhance research quality.
• Developed a reproducible framework for validation.
• Assessed the national CONGRESS data set as a case example.
• Set benchmarks for quality measurement across databases.
• The proposed framework ensures reliability in data validation.
• Sets a standard for high-quality research outcomes.
• Highlights the importance of collaborative data efforts.