A new method for the synthesis of 6,7-dihydro-5 H -pyrrolo2,1- a 2benzazepines and 5,6,7,9,10,11-hexahydro-12 H -indolo2,1- a 2benzazepines and evaluation of their bioactivity | Synapse
January 22, 2026Open Access
A new method for the synthesis of 6,7-dihydro-5 H -pyrrolo2,1- a 2benzazepines and 5,6,7,9,10,11-hexahydro-12 H -indolo2,1- a 2benzazepines and evaluation of their bioactivity
Key Points
To develop a new method for synthesizing specific benzazepine derivatives and evaluate their biological activity.
Utilized a domino reaction for the synthesis of benzazepine derivatives.
Focused on pyrrolo[2,1-a][2]benzazepines and indolo[2,1-a][2]benzazepines.
Performed bioactivity evaluation of the synthesized compounds.
Successfully synthesized various pyrrolo[2,1-a][2]benzazepine and indolo[2,1-a][2]benzazepine derivatives.
Demonstrated potential bioactivity for these new chemical entities.
Abstract
Efficient synthesis of pyrrolo2,1- a 2benzazepine and indolo2,1- a 2benzazepine derivatives via a domino reaction and their bioactivity evaluation.