A ratiometric FRET sensor using Ti 3 C 2 T x MXene for intracellular microRNA-21 quantitative measurement

Key Points

• The aim is to develop a ratiometric FRET biosensor using MXene for detecting intracellular microRNA-21 levels.
• Developed a ratiometric fluorescence biosensor platform using Ti3C2T x MXene nanoparticles.
• Evaluated the sensor's effectiveness in detecting microRNA-21 in intracellular environments.
• Successfully demonstrated the capability to quantitatively measure microRNA-21 using the FRET sensor.
• Showed that the sensor provides reliable fluorescence readings correlating with microRNA-21 concentrations.