Background: Central nervous system (CNS) tumors are distinct due to their origin from specialized tissues and the unique anatomical features of the CNS. Squash smears, frozen sections, and paraffin sections are utilized for histopathological diagnoses. This study aims to analyze the histopathological spectrum of CNS tumors and their clinical profiles. Objectives: To analyze the pathology of CNS tumors based on age, sex, location, incidence, gross and microscopic findings, and characteristic features for differentiation. Materials and Methods: This retrospective study at SBKS Medical Institute and Research Centre, Vadodara, analyzed 50 CNS tumor cases from May 2012 to October 2014, using demographic data, tumor site, histopathological features, and WHO 2016 classification. Results: Among 50 CNS tumor cases, 41 were intracranial and 9 were intraspinal. The male-to-female ratio was 1.17:1, with the highest incidence observed in the fourth decade. Meningiomas were the most common tumors, followed by astrocytic tumors. Conclusion: This study provides valuable data on the epidemiology and histopathological characteristics of CNS tumors. Despite the advancements in neuroimaging techniques, histological examination remains the gold standard for diagnosing various CNS lesions.
Modi et al. (Thu,) studied this question.