Gene therapy is a promising molecular-level treatment for a variety of ailments, including genetic problems. Nanoparticles are essential to the advancement of this treatment. The various roles that nanoparticles play in gene therapy are examined in this abstract, with special attention to their importance in targeted medication administration, increased transfection efficiency, and regulated release of genetic material. Using nanoparticles as carriers for nucleic acids, such as DNA and RNA, is one of the main uses of these particles in gene therapy. Their small size and adaptable surface characteristics allow genetic material to be efficiently encapsulated and protected, allowing for its safe delivery to target cells. The therapeutic efficacy of gene-based therapies is increased and off-target effects are reduced because to this focused delivery. Additionally, by altering their surface to support cellular growth, nanoparticles can get past biological barriers like cell membranes.
Vediya et al. (Wed,) studied this question.