What question did this study set out to answer?

To explore the occurrence of a multilobulated popliteal cyst after total knee arthroplasty and its possible link to a low-virulence infection.

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February 2, 2026

Enlarging, Multilobulated Popliteal Cyst After Total Knee Arthroplasty

Key Points

To explore the occurrence of a multilobulated popliteal cyst after total knee arthroplasty and its possible link to a low-virulence infection.
Case presentation of a 69-year-old woman with a popliteal cyst after TKA.
Magnetic resonance imaging used for diagnosis of the cyst.
Intraoperative cultures were taken during revision TKA to identify the infecting organism.
Initial diagnosis was inconclusive but later confirmed as culture-negative prosthetic joint infection.
Micrococcus luteus was identified during revision surgery.
Complete resolution of the cyst was observed at the 4-year follow-up with minimal pain.

Abstract

Case: A 69-year-old woman presented with a 5-year history of an enlarging popliteal cyst 7 years after total knee arthroplasty (TKA). Magnetic resonance imaging revealed a large, multilobulated popliteal cyst. Initial diagnostic workup was inconclusive but repeat evaluation met criteria for culture-negative prosthetic joint infection (PJI). She underwent revision TKA, intraoperative cultures identified Micrococcus luteus , and she remains on antibiotic suppression. At her 4-year follow-up, she demonstrated complete resolution of the popliteal cyst with minimal pain. Conclusion: Popliteal cysts may represent a primary presenting symptom of PJI, especially when the causative organism is of low virulence, such as M. luteus .

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Enlarging, Multilobulated Popliteal Cyst After Total Knee Arthroplasty

Key Points

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