What question did this study set out to answer?

The aim is to evaluate the effectiveness of various percutaneous coronary intervention strategies for coronary small-vessel disease.

February 6, 2026Open Access

Comparative effectiveness of percutaneous coronary intervention strategies for coronary small-vessel disease: a network meta-analysis of randomized trials

Key Points

The aim is to evaluate the effectiveness of various percutaneous coronary intervention strategies for coronary small-vessel disease.
Conducted a network meta-analysis of randomized trials
Compared effectiveness of different intervention strategies including SES, ZES, EES, and DCB-PTX
Evaluated outcomes based on clinical benefits and effectiveness across different devices
SES demonstrated the most consistent clinical benefit for coronary small-vessel disease
ZES, EES, and DCB-PTX are effective alternatives in selected cases
BMS, POBA, and GPBA showed lower effectiveness

Abstract

SES provides the most consistent clinical benefit for coronary SVD. ZES, EES, and DCB-PTX are effective alternatives in selected settings, whereas BMS, POBA, and GPBA are less effective. These findings offer comparative evidence to guide device selection in SVD.

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Cite This Study

Deng et al. (Tue,) studied this question.

synapsesocial.com/papers/698584f98f7c464f23008480 https://doi.org/https://doi.org/10.1080/07853890.2026.2623329

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