What question did this study set out to answer?

The study aims to evaluate the effects of alteplase, aspirin, and clopidogrel on stroke-related outcomes.

February 8, 2026International Journal of Neuroscience0 citations

Effects of Alteplase, Aspirin, and Clopidogrel on Inflammatory Factors and Neurological Function in Patients with Stroke

YLYang LiNanjing Medical University XYXiaoli YangCounty Hospital ZZZongyou ZhaoBeijing Academy of Artificial Intelligence

Key Result

Triple-agent therapy with alteplase, aspirin, and clopidogrel may improve cognitive outcomes and functional recovery in stroke patients.

Key Points

The study aims to evaluate the effects of alteplase, aspirin, and clopidogrel on stroke-related outcomes.
Investigated the combination of alteplase, aspirin, and clopidogrel in stroke patients
Assessed neurological impairment and cognitive outcomes
Considered cost implications of the triple-agent therapy
Triple-agent therapy reduced neurological impairment
Improved cognitive outcomes and early functional recovery observed
Higher medical costs associated with the treatment

Structured PICO

Does triple-agent therapy with alteplase, aspirin, and clopidogrel improve neurological function and inflammatory factors in patients with stroke?

Population

Patients with stroke

Intervention

Triple-agent therapy with alteplase, aspirin, and clopidogrel

Outcome

Inflammatory factors, neurological impairment, cognitive outcomes, and early functional recovery

Triple-agent therapy with alteplase, aspirin, and clopidogrel may improve neurological and cognitive outcomes in stroke patients, though it increases medical costs.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Triple-agent therapy, with alteplase, aspirin, and clopidogrel, may reduce neurological impairment, improve cognitive outcomes, and enhance early functional recovery in patients with stroke, although at the expense of higher medical costs.

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