The efficacy and safety of high-frequency SMA-rTMS on freezing of gait in patients with Parkinson’s disease: a study protocol for a randomized controlled trial

Key Points

• The research aims to evaluate the efficacy and safety of high-frequency SMA-rTMS in alleviating freezing of gait in patients with Parkinson's disease.
• Conduct a randomized controlled trial registered with standard ethical approvals.
• Target patients diagnosed with Parkinson's disease experiencing freezing of gait.
• Implement high-frequency SMA-rTMS as the primary intervention.
• Compare outcomes against a control group receiving a placebo.
• Anticipated positive effects on reducing freezing of gait episodes.
• Improvement in overall gait performance expected.
• Safety and side effects of the intervention will be closely monitored.