CTI ablation with linear PFA catheter shows safety and efficacy similar to RF ablation but with greater procedural efficiency.
Does bipolar linear pulsed field ablation provide similar safety and efficacy compared to standard radiofrequency ablation for cavotricuspid isthmus ablation in patients with typical atrial flutter?
Linear pulsed field ablation for cavotricuspid isthmus ablation in typical atrial flutter appears to offer similar safety and efficacy to standard radiofrequency ablation, but with greater procedural efficiency.
Absolute Event Rate: 0% vs 0%
This subanalysis of ADVANTAGE AF extends the primary results by allowing comparison of bipolar linear PFA and RF ablation for CTI, integrating preclinical lesion modeling with clinical dosing, and establishing a standardized reliable coronary safety protocol. Although not randomized comparisons, these findings suggest that CTI ablation with a linear PFA catheter is associated with safety and efficacy similar to RF ablation and greater efficiency. (A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation ADVANTAGE AF; NCT05443594).
Part of April 14 2026 JACC release batch on PFA and AF; high interest in pulsed field technology as safer alternative to thermal ablation. Conference and journal buzz in electrophysiology community.
Gerstenfeld et al. (Fri,) reported a other. CTI ablation with linear PFA catheter shows safety and efficacy similar to RF ablation but with greater procedural efficiency.