Efficacy and safety of high-definition transcranial direct current stimulation combined with digital rehabilitation on upper limb function in stroke patients: study protocol for a randomized, double-blind, sham-controlled confirmatory trial

Key Points

• The central aim is to assess the efficacy and safety of high-definition transcranial direct current stimulation in improving upper limb function after stroke.
• Conduct a randomized, double-blind, sham-controlled trial
• Participants include stroke patients
• Intervention combines stimulation with digital rehabilitation
• Outcomes focus on upper limb functionality
• Expected improvements in upper limb function
• Safety profile monitored throughout the trial